EPIC Study design1

36 centres

centres

360 dogs

dogs

Double-blinded Placebo-controlled

double-blinded placebo-controlled

11 countries

countries

Over 5 years

years

Building on the groundwork laid by the QUEST Study, EPIC is the largest prospective, randomised clinical study in veterinary cardiology (regarding both study time and total days in study).

  • Led by independent cardiologists
  • High-quality, robust dataset
  • Comparable in size to many studies of human patients with cardiovascular disease

Epic study inclusion criteria

Echocardiographic evidence of advanced MMVD Dogs 6 years of age or older Characteristic systolic heart murmur greater than or equal to grade 3/6
Body weight between 4.1 kg and 15 kg Evidence of cardiac enlargement

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